Zhang Jinpeng, Wu Xiuwen, Ren Huajian, Zheng Tao, Ke Jia, Chen Yao, Li Ranran, Yin Wei, Zhou Shaoying, Wang Liuhua, Zeng Qingjun, Dong Jianzhong, Ren Jian'an
Objective To analyze the etiologic composition and age distribution of acute abdomen cases registered in the Surgical Rescue Network, and to provide evidence for stratified management of acute abdomen and the development of a regional acute care surgery (ACS) system. Methods A retrospective analysis was performed using registry data from the Surgical Rescue Network from January 2024 to December 2025. Case contributions from participating centers and the composition of ACS-related cases were described. Diagnoses of acute abdomen were standardized and categorized. The major etiologies, baseline characteristics, and etiologic composition across different age groups were compared. Continuous variables are presented as median (interquartile range), and categorical variables are presented as number of cases and percentage. Results A total of 24,877 ACS-related cases were registered, including 21,098 cases of acute abdomen (84.8%). Acute appendicitis-related diseases were the most common (13,082 cases, 62.0%), followed by gallbladder and biliary emergencies (2,915 cases, 13.8%), gastrointestinal perforation (2,170 cases, 10.3%), intestinal obstruction and hernia-related emergencies (1,857 cases, 8.8%), and acute pancreatitis (591 cases, 2.8%). These five categories accounted for 97.7% of all cases. Among 21,070 patients with non-missing age data, the proportion of acute appendicitis-related diseases decreased with increasing age, whereas the combined proportion of gallbladder and biliary emergencies, gastrointestinal perforation, and intestinal obstruction and hernia-related emergencies increased from 6.1% in the < 18-year group to 67.7% in the ≥ 80-year group. Etiologic groups such as perforation and intestinal obstruction/hernia-related emergencies carried a relatively higher anesthesia risk burden. Conclusion The acute abdomen cases registered in the Surgical Rescue Network exhibit two distinct features: a concentration of high-frequency diseases and an increased burden of complex etiologies and risk in older patients. Acute appendicitis-related diseases predominate in younger patients, whereas perforation, obstruction, and gallbladder/biliary emergencies increase markedly in older patients. These findings may inform stratified management of acute abdomen, pathway design for abdominal pain centers, and allocation of regional ACS resources.